Secretory IgA
Secretory
Immunoglobulin A (sIgA)
Imbalanced secretory
IgA (sIgA) levels may provide the link between
gut imbalances and systemic illness. SIgA is
found throughout the
gastrointestinal tract, and in mucus
secretions throughout the body. This
important immunoglobulin is the first line of defence against
bacteria, food residues, fungi, parasites
and viruses, and a deficiency of sIgA is common.
Low levels can make us
more susceptible to infection and may be a
fundamental cause of asthma, autoimmune
conditions, Coeliac Disease, chronic
infections, Crohn's Disease, candidiasis,
food intolerances, allergies, autism and
other behavioural problems. Very high levels
of sIgA can also be found in people who have chronic
infections and whose immune system is
overloaded or hypersensitive. Lifestyle, stress and
nutritional factors can all influence sIgA
levels.
Functions of
sIgA
- Immunity: sIgA reduces the uptake
of enteric food molecules, bacterial
toxins and other macro molecules
- Anti-inflammatory
- Viral neutralisation
- Plasmid elimination
- Inhibition of pathogenic
colonisation
Who
should test sIgA?
Deficiencies or low levels may be associated
with asthma, autoimmune disease, high stress levels, high antibiotic use, candidiasis,
Coeliac Disease, autism, food
allergies/intolerances, Ulcerative Colitis & Crohns
Disease. Individuals with sIgA deficiency usually
show varying degrees of nutrient
malabsorption and are susceptible to food
allergies.
Pricing
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